Entacapone Tablets
Active Ingredients: Entacapone
Other Names: Comtan Tablets
Drug Class: COMT Inhibitors
Rx Status: Available by prescription only
Generic Available: No
Product Images & Descriptions: 
What is/are Entacapone Tablets?
What should I tell my health care providers before I take this medicine?
How should I use this medicine?
What if I miss a dose?
What may interact with this medicine?
What side effects may I notice from this medicine?
What should I watch for while using this medicine?
Where should I keep this medicine?
What is/are Entacapone Tablets?
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ENTACAPONE is used in combination with levodopa-carbidopa therapy to treat Parkinson's disease.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care providers before I take this medicine?
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They need to know if you have any of these conditions: - liver disease
- an unusual or allergic reaction to entacapone, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
- breast-feeding
How should I use this medicine?
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Take this medicine by mouth with a glass of water at the same time you take your levodopa-carbidopa. Follow the directions on the prescription label. You can take this medicine with or without food. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
Note: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
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Do not take this medicine with any of the following: - isoniazid
- medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
- procarbazine
This medicine may also interact with the following:- ampicillin
- apomorphine
- bitolterol
- cholestyramine
- chloramphenicol
- dopamine, dobutamine
- epinephrine, norepinephrine
- erythromycin
- isoetharine
- isoproterenol
- methyldopa
- probenecid
- rifampicin
This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What side effects may I notice from this medicine?
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Side effects that you should report to your doctor or health care professional as soon as possible: - allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- confusion
- decrease in urination
- feeling faint or lightheaded, falls
- fever
- hallucinations
- involuntary muscle movements
- sore muscles
- stomach pain
- vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):- constipation or diarrhea
- drowsiness or fatigue
- nausea
- upset stomach
This list may not describe all possible side effects.
What should I watch for while using this medicine?
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This medicine may also increase the side effects caused by levodopa-carbidopa like nausea or restless movements. If you notice an increase in or the appearance of certain side effects, contact your physician. The dose of levodopa-carbidopa may need to be lowered. Do not decrease your medicine dose without asking your doctor or health care professional.
You may get dizzy or have difficulty controlling your movements. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks. Dizziness and sleepiness are more common at the beginning of treatment with this medicine.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
This medicine may cause urine to look dark yellow to orange or brown in color. This is normal and is not cause for concern.
Where should I keep this medicine?
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Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Last Updated:June 19, 2007 COPYRIGHT© Gold Standard, An Elsevier Company |
